Ongoing Projects
Research Vision: Reprogramming Intercellular Communication and Multicellular Circuits for Synthetic Bacterial Communities
Research Question: How may the variability of intrinsic variables of interspecies systems impact community behavior using thermodynamic and kinetic models?
Research Question: What design rules can improve the predictive Co-design of synthetic communities and artificial microfluidic micro-environments for user-defined community behavior?
Research Topic: Microfluidic Chip Design, Manufacturing, and Assay (Microscope) Automation
Project: CAD-based Movement & Deep-learning Image Analysis
Fund: NSF Grant - Ongoing Research Projects
Research Vision: Engineering High-throughput Microfluidic Chips to Enable the Dynamic Study and Characterization of Microbial Communities
Research Question: How can large circuits be proposed as multicellular small-in-size sub-circuits in microbial communities? How can their properties be used as design rules to predict desirable states precisely?
Research Topic: Microfluidic Chip Design, Manufacturing, and Assay (Microscope) Automation
Project: Chip-chip Network Chips and Design Automation for Multiple-species studies
Fund: NSF Grant - Ongoing Research Projects
Research Vision: Reprogramming synthetic communities and engineering deployable microfluidic chips to monitor heavy metals in the soil microbiome
Research Question: How microfluidic primitive properties (i.e., structure and dynamics) can be scalable to larger networks of primitives in a predictive way when implementing monolayer and multi-layer (with complex routing and microfluidic technology integration) fabrication approaches?
Research Question: How does the variability of such extrinsic variables impact cell growth dynamics and community behavior using fluidic-dynamic models with microfluidic properties and variables of microfluidic-based micro-environments?
Research Topic: Microfluidic Chip Assembly Technology Integration
Project: Engineering microbes and controllable micro-environments for sustainable food systems
Fund: STEM Pathways Outreach Program
Collaboration: BU-iGEM 2023
Research Vision: Develop complex multi-layer chips (microbes-plant tissue interaction) to study how synthetic microbes can control plants fighting diseases
Research Vision: Assembling robust isolated microbes dispersed as scalable, beneficial microbes to help plants fight diseases in plant microbiome
Research Question: What communication and gene expression variables influence microbial community dynamics, functional activities, and spatial structure in controlled environmental contexts?
Ongoing Collaborations
Research Topic: Microfluidic and Semiconductor Technology Interfaces
Project: Fabricating IR transparent CaF2-PDMS microfluidic device
Collaboration: DAMP Support - Cheng/Derrick/BU
Research Topic: Microfluidic and Semiconductor Technology Interfaces
Project: PhotoSense – monolithically integrated photonic-electronic platform for bio-sensing
Project: Integrating uF and Gold-electrode Microfabrication (single Si-wafer)
Collaboration: DAMP Support - Dorde/BU
Research Topic: Biosensors and Microfluidic Automation for Real-life Applications
Project: Commercially-available electrodes integration into microfluidics
Fund: BIOMADE - Rabia/DAMP Collaboration and CAPRA Industry Partnership
Collaboration: Doroth - Patent with FMC and Genesis - Industry Partnerships
Translational Research
Research Topic: Biosensors and Microfluidic Automation for Real-life Applications
Doroth Services - Detection and Monitoring of Pathogens and Beneficial Microbes in the Soil Microbiome
Research Topic: Biosensors and Microfluidic Automation for Real-life Applications
Doroth - New IPs - Industry Partnerships - High-risk, hi -reward Research Sponsorships
