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Course 2: Advanced Microfluidics 

Syllabus

Lectures:

1: Introduction to MEMS and Microfabrication

2: Introduction to Microfluidic Laws and Hydrodynamics

3: Miniaturization Principles and Challenges

4: Microfluidic Hydrodynamics: Viscous Flow, Surface Tension, and the Problem of Mixing

5: Microfluidic Hydrodynamics: Electrokinetic Flows

6: Engineering of Surfaces in Micro/Nano Devices, Surface Wetting

7: Microfluidic Design and Fabrication Tools and Infrastructure

8: Machine-learning methods for Microfluidic Design Automation

9: Introduction to 3D Printing, CNC Milling, and Laser-cutting for Microfluidics Applications

10: Soft-lithography Fabrication Processes and Profilometer

11: Microscope Techniques for Microfluidics Testing and Bioassays

12: MEMS Applications and Product Design

Labs:

1: Hands-on: Lab Safety Review and Best Practices

2: Hands-on: Microfluidic Design Tools, Rules, and Protocols

3: Hands-on: COMSOL Simulation Set-up

4: Hands-on: COMSOL Simulation Operation Units, Mixes, Multiplexes

5: Hands-on: CNC Milling Fabrication and Cleaning Techniques

6: Hands-on: Laser-cutting Fabrication and Solenoid Activation

7: Demo: Cleanroom work: Overall Training

8: Demo: Cleanroom work - Mask writer

9: Demo: Cleanroom work - Spin disk and Mask Aligner (single layer)

10: Hands-on: Microscope & Microfluidics Setup: Testing Device

Workload:

3 MSU -> 3h/w -> 1h Lecture/week + 2h Labs/week

12 Lectures + 10 Labs -> 22 Interactions

Full semester (14 weeks): 12 weeks + Midterms + Projects

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Score - 0-100 points:

  • 5% Attendance

  • 10% Quizzes (once/week) 

  • 30% Assignments (Lab reports)

  • 15% Mid-term Exam (half-semester)

  • 40% Final Projects (end-semester) -> Total 100%

5% BONUS Scores During Lab Sessions (Extra work)

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Course Materials

  • Open-source scientific papers (TBI)

  • Free/Accessible Textbooks (TBI)

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Final Grade Range (90-100->A, etc. - subject to change)

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Late Policy (10% off a grade per delayed day)

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